How can supercomputers help us fight this virus? These high-performance computing systems allow researchers to run very large numbers of calculations in epidemiology, bioinformatics, and molecular modeling. These experiments would take years to complete if worked by hand, or months if handled on slower, traditional computing platforms.
As a powerful example of the potential, IBM’s Summit, the most powerful supercomputer on the planet, has already enabled researchers at the Oak Ridge National Laboratory and the University of Tennessee to screen 8,000 compounds to find those that are most likely to bind to the main “spike” protein of the coronavirus, rendering it unable to infect host cells. They were able to recommend the 77 promising small-molecule drug compounds that could now be experimentally tested. This is the power of accelerating discovery through computation.