Well it doesen't sound like an easy opening match, but after all, this is a WTA event so you can't expect an easy ride. But I believe Ana has a really nice chance for a win here, she's not only seeded (so she's supposed to win this match) but she also seems to be in a much better form than Hofmanova right now, eventhough Hofmanova has a better c-h. In Shrewsbury 75k two weeks ago, Ana beat Minella (WTA #133) in straights and took a set from Kremer who in the previous round beat Hofmanova 2 & 1.
So just get your game going Ana, and make sure you don't blow this chance. Good luck
Ana is playing in next week's Istanbul $25K, where she's the #6 seed. Unfortunately she got one of the strongest opponents in R1: Kristyna Pliskova, who I believe is the second highest-ranked among the non-seeded players.