I think the outcome depends on which Lindsay shows up. If a determined Lindsay shows up that is willing to play her game and fight then I say the match could go either way. But if the tenative Lindsay shows up, then I say Serena wins easily in 2 sets.
It depends which Lindsay and which Serena shows up. But I think that Serena is extra guarded at this tourney because she doesn't want to go out to anyone (like last year), so I think she will be very focused. Also, Lindsay has always had a hard time with Serena, ever since the beginning of their H2H. Serena has always been a hard player for Lindsay...and since Serena's confidence is high and this is on clay, it doesn't bode well for Lindsay. I say the first set will be tight, the second set won't be. Serena in two straight sets.